nomic-embed text-v1.5 Clinical-Trials Matryoshka

This is a sentence-transformers model finetuned from nomic-ai/nomic-embed-text-v1.5 on the Clinical_trials_anchor-positive-pairs_EmbeddingModel-data2 dataset. It maps sentences & paragraphs to a 768-dimensional dense vector space and can be used for semantic textual similarity, semantic search, paraphrase mining, classification, clustering, and more.

Model Details

Model Description

• Model Type: Sentence Transformer
• Base model: nomic-ai/nomic-embed-text-v1.5
• Maximum Sequence Length: 8192 tokens
• Output Dimensionality: 768 dimensions
• Similarity Function: Cosine Similarity
• Supported Modality: Text
• Training Dataset: Clinical_trials_anchor-positive-pairs_EmbeddingModel-data2
• Language: en
• License: apache-2.0

Model Sources

• Documentation: Sentence Transformers Documentation
• Repository: Sentence Transformers on GitHub
• Hugging Face: Sentence Transformers on Hugging Face

Full Model Architecture

SentenceTransformer(
  (0): Transformer({'transformer_task': 'feature-extraction', 'modality_config': {'text': {'method': 'forward', 'method_output_name': 'last_hidden_state'}}, 'module_output_name': 'token_embeddings', 'architecture': 'NomicBertModel'})
  (1): Pooling({'embedding_dimension': 768, 'pooling_mode': 'mean', 'include_prompt': True})
)

Usage

Direct Usage (Sentence Transformers)

First install the Sentence Transformers library:

pip install -U sentence-transformers

Then you can load this model and run inference.

from sentence_transformers import SentenceTransformer

# Download from the 🤗 Hub
model = SentenceTransformer("vab46/nomic-embed-text-v1.5_Clinical-Trials_Matryoshka2")
# Run inference
documents = [
    '* 0-12 months of age. (Must be less than 1 year of life for the pulse oximeter portion of the study) Weight greater than 2 Kg at time of study\n* Admitted to an intensive care unit. (Not applicable for outpatient cohort)\n* Arterial line in place as standard of care (Not applicable for outpatient cohort)\n* Informed consent provided by parent or LAR.\n\n',
]
queries = [
    'What age group is targeted for this clinical trial?',
    'What is the focus of this clinical trial?',
    'Are patients with ASA physical status IV excluded from participating in this study?',
]
query_embeddings = model.encode_query(queries)
document_embeddings = model.encode_document(documents)
print(query_embeddings.shape, document_embeddings.shape)
# [1, 768] [3, 768]

# Get the similarity scores for the embeddings
similarities = model.similarity(query_embeddings, document_embeddings)
print(similarities)
# tensor([[ 0.4220, -0.1157,  0.1650]])

Evaluation

Metrics

Information Retrieval

• Dataset: dim_768, dim_512, dim_256, dim_128, dim_64
• Evaluated with InformationRetrievalEvaluator with these parameters:

Comparison with the baseline model performance on same data

Training Details

Training Dataset

json

• Dataset: json
• Size: 7,869 training samples
• Columns: positive and anchor
• Approximate statistics based on the first 100 samples:

  	positive	anchor
  type	string	string
  modality	text	text
  details	min: 11 tokensmean: 132.52 tokensmax: 1135 tokens	min: 10 tokensmean: 15.27 tokensmax: 34 tokens

• Samples:

  positive	anchor
  * - Age 18 years or older* Biopsy-proven primary IgA nephropathy or primary focal segmental glomerulosclerosis* Stable kidney function with an estimated glomerular filtration rate greater than 30 mL/min/1.73 m²* Availability of serum and urine samples for soluble CD163 measurement* Availability of relevant demographic, clinical, laboratory, histopathologic, and follow-up data* For the healthy control group: age- and sex-matched individuals without known chronic disease and with normal kidney function* Written informed consent	What are the specific kidney diseases included in this clinical trial?
  * Written informed consent obtained and documented by the participant's signature.* Age ≥18 years at the time of consent.* Clinically established or suspected diagnosis or recurrence of an oncologic or non-oncologic disease as defined in chapter 7.1 of study protocol.* Availability of standard-of-care imaging (e.g., clinically established PET tracer or anatomical imaging such as CT/MRI) to allow comparative evaluation.	What type of cancer or non-cancerous condition are participants diagnosed with?
  * Patients aged 16 years or older at the time of debonding* Treatment plan of extraction or non-extraction followed by straight wire appliances in the upper arch only or both arches* Undergone expansion treatment in the upper arch causing an arch width increase of 3-10mm, either using a Quadhelix, expansion with archwires, or URA with midline screw* Had pretreatment dental cast* Had no chronic medical condition.	What is the minimum age requirement for patients in this clinical trial?

• Loss: MatryoshkaLoss with these parameters:

  {
      "loss": "MultipleNegativesRankingLoss",
      "matryoshka_dims": [
          768,
          512,
          256,
          128,
          64
      ],
      "matryoshka_weights": [
          1,
          1,
          1,
          1,
          1
      ],
      "n_dims_per_step": -1
  }
  

Training Hyperparameters

Non-Default Hyperparameters

• num_train_epochs: 4
• learning_rate: 2e-05
• lr_scheduler_type: cosine
• warmup_steps: 0.1
• gradient_accumulation_steps: 4
• fp16: True
• per_device_eval_batch_size: 32
• load_best_model_at_end: True
• batch_sampler: no_duplicates

All Hyperparameters

• per_device_train_batch_size: 8
• num_train_epochs: 4
• max_steps: -1
• learning_rate: 2e-05
• lr_scheduler_type: cosine
• lr_scheduler_kwargs: None
• warmup_steps: 0.1
• optim: adamw_torch_fused
• optim_args: None
• weight_decay: 0.0
• adam_beta1: 0.9
• adam_beta2: 0.999
• adam_epsilon: 1e-08
• optim_target_modules: None
• gradient_accumulation_steps: 4
• average_tokens_across_devices: True
• max_grad_norm: 1.0
• label_smoothing_factor: 0.0
• bf16: False
• fp16: True
• bf16_full_eval: False
• fp16_full_eval: False
• tf32: None
• gradient_checkpointing: False
• gradient_checkpointing_kwargs: None
• torch_compile: False
• torch_compile_backend: None
• torch_compile_mode: None
• use_liger_kernel: False
• liger_kernel_config: None
• use_cache: False
• neftune_noise_alpha: None
• torch_empty_cache_steps: None
• auto_find_batch_size: False
• log_on_each_node: True
• logging_nan_inf_filter: True
• include_num_input_tokens_seen: no
• log_level: passive
• log_level_replica: warning
• disable_tqdm: False
• project: huggingface
• trackio_space_id: None
• trackio_bucket_id: None
• trackio_static_space_id: None
• per_device_eval_batch_size: 32
• prediction_loss_only: True
• eval_on_start: False
• eval_do_concat_batches: True
• eval_use_gather_object: False
• eval_accumulation_steps: None
• include_for_metrics: []
• batch_eval_metrics: False
• save_only_model: False
• save_on_each_node: False
• enable_jit_checkpoint: False
• push_to_hub: False
• hub_private_repo: None
• hub_model_id: None
• hub_strategy: every_save
• hub_always_push: False
• hub_revision: None
• load_best_model_at_end: True
• ignore_data_skip: False
• restore_callback_states_from_checkpoint: False
• full_determinism: False
• seed: 42
• data_seed: None
• use_cpu: False
• accelerator_config: {'split_batches': False, 'dispatch_batches': None, 'even_batches': True, 'use_seedable_sampler': True, 'non_blocking': False, 'gradient_accumulation_kwargs': None}
• parallelism_config: None
• dataloader_drop_last: False
• dataloader_num_workers: 0
• dataloader_pin_memory: True
• dataloader_persistent_workers: False
• dataloader_prefetch_factor: None
• dataloader_multiprocessing_context: None
• dataloader_in_order: True
• remove_unused_columns: True
• label_names: None
• train_sampling_strategy: random
• length_column_name: length
• ddp_find_unused_parameters: None
• ddp_bucket_cap_mb: None
• ddp_broadcast_buffers: False
• ddp_static_graph: None
• ddp_backend: None
• ddp_timeout: 1800
• fsdp: None
• fsdp_config: None
• deepspeed: None
• debug: []
• skip_memory_metrics: True
• do_predict: False
• resume_from_checkpoint: None
• local_rank: -1
• prompts: None
• batch_sampler: no_duplicates
• multi_dataset_batch_sampler: proportional
• router_mapping: {}
• learning_rate_mapping: {}
• warmup_ratio: None

Training Logs

• The bold row denotes the saved checkpoint.

Training Time

• Training: 26.0 minutes

Framework Versions

• Python: 3.13.15
• Sentence Transformers: 5.7.0
• Transformers: 5.15.0
• PyTorch: 2.11.0+cu128
• Accelerate: 1.14.0
• Datasets: 4.0.0
• Tokenizers: 0.22.2

Additional Resources

• Training and Finetuning Embedding Models with Sentence Transformers: the end-to-end guide for training or finetuning Sentence Transformer models.
• Introduction to Matryoshka Embedding Models: variable-size embeddings that can be truncated with minimal quality loss.
• Binary and Scalar Embedding Quantization for Significantly Faster & Cheaper Retrieval: post-training compression of embedding vectors.
• Multimodal Embedding & Reranker Models with Sentence Transformers: use text, image, audio, and video models through the same API.
• Training and Finetuning Multimodal Embedding & Reranker Models with Sentence Transformers: train multimodal embedding models, with a Visual Document Retrieval walkthrough.

Citation

BibTeX

Sentence Transformers

@inproceedings{reimers-2019-sentence-bert,
    title = "Sentence-BERT: Sentence Embeddings using Siamese BERT-Networks",
    author = "Reimers, Nils and Gurevych, Iryna",
    booktitle = "Proceedings of the 2019 Conference on Empirical Methods in Natural Language Processing",
    month = "11",
    year = "2019",
    publisher = "Association for Computational Linguistics",
    url = "https://arxiv.org/abs/1908.10084",
}

MatryoshkaLoss

@misc{kusupati2024matryoshka,
    title={Matryoshka Representation Learning},
    author={Aditya Kusupati and Gantavya Bhatt and Aniket Rege and Matthew Wallingford and Aditya Sinha and Vivek Ramanujan and William Howard-Snyder and Kaifeng Chen and Sham Kakade and Prateek Jain and Ali Farhadi},
    year={2024},
    eprint={2205.13147},
    archivePrefix={arXiv},
    primaryClass={cs.LG}
}

MultipleNegativesRankingLoss

@misc{oord2019representationlearningcontrastivepredictive,
      title={Representation Learning with Contrastive Predictive Coding},
      author={Aaron van den Oord and Yazhe Li and Oriol Vinyals},
      year={2019},
      eprint={1807.03748},
      archivePrefix={arXiv},
      primaryClass={cs.LG},
      url={https://arxiv.org/abs/1807.03748},
}